Chapter 2. Prefatory Chapter: The Importance of the Autoantibody-defined Epitope
- Prof. Dr. K. Michael Pollard
Published Online: 31 MAY 2006
DOI: 10.1002/3527607854.ch2
Copyright © 2006 Wiley-VCH Verlag GmbH & Co. KGaA
Book Title
Autoantibodies and Autoimmunity: Molecular Mechanisms in Health and Disease
Additional Information
How to Cite
Tan, E. M. (2006) Prefatory Chapter: The Importance of the Autoantibody-defined Epitope, in Autoantibodies and Autoimmunity: Molecular Mechanisms in Health and Disease (ed K. M. Pollard), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527607854.ch2
Editor Information
Department of Molecular and Experimental Medicine, The Scripps Research Institute, MEM 131, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
Publication History
- Published Online: 31 MAY 2006
- Published Print: 25 NOV 2005
ISBN Information
Print ISBN: 9783527311415
Online ISBN: 9783527607853
- Summary
- Chapter
Keywords:
- autoantibodies;
- autoimmunity;
- autoepitope;
- autoantibody-defined antigenic determinant
Summary
This chapter contains sections titled:
Introduction
The Uniqueness of the Autoantibody-defined Antigenic Determinant or the Autoepitope
The Highly Conserved Nature of the Autoepitope
The Autoepitope Resides at or in Close Proximity to the Functional Region or Binding Site of the Antigen
The Autoepitope is Composed of Conformation-dependent Discontinuous Sequences of the Antigen
Conclusions