Chapter 23. Genetics of Autoantibody Production in Mouse Models of Lupus

  1. Prof. Dr. K. Michael Pollard
  1. Dwight H. Kono,
  2. Argyrios N. Theofilopoulos

Published Online: 31 MAY 2006

DOI: 10.1002/3527607854.ch23

Book Title

Autoantibodies and Autoimmunity: Molecular Mechanisms in Health and Disease

Autoantibodies and Autoimmunity: Molecular Mechanisms in Health and Disease

Additional Information

How to Cite

Kono, D. H. and Theofilopoulos, A. N. (2006) Genetics of Autoantibody Production in Mouse Models of Lupus, in Autoantibodies and Autoimmunity: Molecular Mechanisms in Health and Disease (ed K. M. Pollard), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527607854.ch23

Editor Information

  1. Department of Molecular and Experimental Medicine, The Scripps Research Institute, MEM 131, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA

Author Information

  1. The Scripps Research Institute, Department of Immunology, 10550 N. Torrey Pines Road, La Jolla, CA 92037, USA

Publication History

  1. Published Online: 31 MAY 2006
  2. Published Print: 25 NOV 2005

ISBN Information

Print ISBN: 9783527311415

Online ISBN: 9783527607853

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CHAPTER TOOLS

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Keywords:

  • genetics of autoantibody production in mouse models of lupus;
  • identifying genes predisposing to systemic autoimmunity;
  • lupus quantitative trait loci

Summary

This chapter contains sections titled:

  • Introduction

  • Identifying Genes Predisposing to Systemic Autoimmunity

  • Mouse Models of SLE in Mapping Studies

  • Lupus Quantitative Trait Loci

  • Loci in NZB, NZW, and NZBxNZW Recombinant Inbred Mice

  • Loci Identified in Crosses of MRL-FaslprMice

  • Loci in BXSB Crosses

  • Loci in Other Spontaneous Lupus Crosses

  • Loci Identified in Induced or Mutant Models of Lupus

  • Conclusions

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