Chapter 10. Case Study of Lacidipine in the Research of New Calcium Antagonists

  1. Dr. János Fischer2,
  2. Prof. Dr. C. Robin Ganellin3
  1. Giovanni Gaviraghi

Published Online: 22 MAY 2006

DOI: 10.1002/3527608001.ch10

Book Title

Analogue-based Drug Discovery

Analogue-based Drug Discovery

Additional Information

How to Cite

Gaviraghi, G. (2006) Case Study of Lacidipine in the Research of New Calcium Antagonists, in Analogue-based Drug Discovery (eds J. Fischer and C. R. Ganellin), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527608001.ch10

Editor Information

  1. 2

    Gedeon Richter Ltd., P.O. Box 27, H-1475 Budapest 10, Hungary

  2. 3

    University College London, Department of Chemistry, 20 Gordon Street, London WC1H OAJ, UK

Author Information

  1. Sienabiotech SpA, Via Fiorentina, 1, 53100 Siena, Italy

Publication History

  1. Published Online: 22 MAY 2006
  2. Published Print: 20 JAN 2006

ISBN Information

Print ISBN: 9783527312573

Online ISBN: 9783527608003

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CHAPTER TOOLS

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Keywords:

  • analogue-based drug discovery;
  • case study of Lacidipine;
  • pharmacological profile;
  • research of new calcium antagonists;
  • Dihydropyridine calcium channel-blocking agents

Summary

This chapter contains sections titled:

  • Introduction

  • Dihydropyridine Calcium Channel-Blocking Agents

    • Nifedipine

    • Felodipine

    • Isradipine

    • Nimodipine

    • Nisoldipine

    • Amlodipine

    • Lacidipine

    • Lercanidipine

    • Manidipine

  • Lacidipine: A Long-Lasting Calcium Channel-Blocking Drug: Case Study

    • The Lacidipine Project

    • Synthesis

    • The Pharmacological Profile of Lacidipine

  • Conclusion

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