Chapter 3. Privileged Structures and Analogue-Based Drug Discovery

  1. Dr. János Fischer2,
  2. Prof. Dr. C. Robin Ganellin3
  1. Hugo Kubinyi

Published Online: 22 MAY 2006

DOI: 10.1002/3527608001.ch3

Analogue-based Drug Discovery

Analogue-based Drug Discovery

How to Cite

Kubinyi, H. (2006) Privileged Structures and Analogue-Based Drug Discovery, in Analogue-based Drug Discovery (eds J. Fischer and C. R. Ganellin), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527608001.ch3

Editor Information

  1. 2

    Gedeon Richter Ltd., P.O. Box 27, H-1475 Budapest 10, Hungary

  2. 3

    University College London, Department of Chemistry, 20 Gordon Street, London WC1H OAJ, UK

Author Information

  1. retired from BASF AG, Donnersbergstraße 9, 67256 Weisenheim am Sand, Germany

Publication History

  1. Published Online: 22 MAY 2006
  2. Published Print: 20 JAN 2006

ISBN Information

Print ISBN: 9783527312573

Online ISBN: 9783527608003

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Keywords:

  • analogue-based drug discovery;
  • privileged structures;
  • side effects;
  • agonists and antagonists;
  • drug action on target classes;
  • GPCR ligands;
  • nuclear receptor ligands;
  • integrin ligands;
  • kinase inhibitors;
  • phosphodiesterase inhibitors;
  • neurotransmitter uptake inhibitors

Summary

This chapter contains sections titled:

  • Introduction

  • Drugs from Side Effects

  • Agonists and Antagonists

  • Privileged Structures

  • Drug Action on Target Classes

    • GPCR Ligands

    • Nuclear Receptor Ligands

    • Integrin Ligands

    • Kinase Inhibitors

    • Phosphodiesterase Inhibitors

    • Neurotransmitter Uptake Inhibitors

  • Summary and Conclusions