Chapter 1. Roles of Hes bHLH Factors in Neural Development

  1. Prof. Dr. Gerald Thiel
  1. Ryoichiro Kageyama1,
  2. Jun Hatakeyama2 and
  3. Toshiyuki Ohtsuka1

Published Online: 22 MAY 2006

DOI: 10.1002/3527608036.ch1

Transcription Factors in the Nervous System: Development, Brain Function, and Diseases

Transcription Factors in the Nervous System: Development, Brain Function, and Diseases

How to Cite

Kageyama, R., Hatakeyama, J. and Ohtsuka, T. (2005) Roles of Hes bHLH Factors in Neural Development, in Transcription Factors in the Nervous System: Development, Brain Function, and Diseases (ed G. Thiel), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527608036.ch1

Editor Information

  1. Department of Medical Biochemistry and Molecular Biology, University of Saarland Medical Center, Building 44, 66421 Homburg, Germany

Author Information

  1. 1

    Institute for Virus Research, Kyoto University, Shogoin-Kawahara, Sakyo-ku, Kyoto 606-8507, Japan

  2. 2

    Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto 860-0811, Japan

Publication History

  1. Published Online: 22 MAY 2006
  2. Published Print: 16 DEC 2005

ISBN Information

Print ISBN: 9783527312856

Online ISBN: 9783527608034

SEARCH

Keywords:

  • transcription factors;
  • neural development;
  • roles of Hes bHLH factors;
  • structure and transcriptional activities;
  • regulation of Hes gene expression;
  • expression of Hes genes;
  • maintenance of neural stem cells;
  • promotion of gliogenesis;
  • maintenance of isthmic organizer

Summary

This chapter contains sections titled:

  • Abstract

  • Introduction

  • Structure and Transcriptional Activities of Hes Factors

  • Regulation of Hes Gene Expression

  • Expression of Hes Genes in the Developing Nervous System

  • Maintenance of Neural Stem Cells by Hes Genes

  • Promotion of Gliogenesis by Hes Genes

  • Maintenance of the Isthmic Organizer by Hes Genes

  • Perspective

  • Acknowledgments

  • Abbreviations