Chapter 4. Functions of LIM-Homeodomain Proteins in the Development of the Nervous System

  1. Prof. Dr. Gerald Thiel
  1. Yangu Zhao1,
  2. Nasir Malik2 and
  3. Heiner Westphal2

Published Online: 22 MAY 2006

DOI: 10.1002/3527608036.ch4

Transcription Factors in the Nervous System: Development, Brain Function, and Diseases

Transcription Factors in the Nervous System: Development, Brain Function, and Diseases

How to Cite

Zhao, Y., Malik, N. and Westphal, H. (2005) Functions of LIM-Homeodomain Proteins in the Development of the Nervous System, in Transcription Factors in the Nervous System: Development, Brain Function, and Diseases (ed G. Thiel), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527608036.ch4

Editor Information

  1. Department of Medical Biochemistry and Molecular Biology, University of Saarland Medical Center, Building 44, 66421 Homburg, Germany

Author Information

  1. 1

    Laboratory of Mammalian Genes and Development, National Institute of Child Health and National Institutes of Health, 6 Center Drive, Bethesda, Maryland 20892-2790, USA

  2. 2

    Laboratory of Mammalian Genes and Development, National Institute of Child Health and Human Development, 6 Center Drive, Bethesda, Maryland 20892-2790, USA

Publication History

  1. Published Online: 22 MAY 2006
  2. Published Print: 16 DEC 2005

ISBN Information

Print ISBN: 9783527312856

Online ISBN: 9783527608034

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Keywords:

  • transcription factors;
  • neural development;
  • functions of LIM-homeodomain proteins;
  • structural features of LIM-HD proteins;
  • classification of LIM-HD proteins;
  • LIM-HD proteins;
  • development of invertebrate nervous systems;
  • development of vertebrate nervous systems;
  • factors that interact;
  • downstream targets

Summary

This chapter contains sections titled:

  • Abstract

  • Introduction

  • Common Structural Features and Classification of LIM-HD Proteins

  • LIM-HD Proteins and the Development of Invertebrate Nervous Systems

    • C. elegans

    • Drosophila

  • Functions of LIM-HD Proteins in the Development of Vertebrate Nervous Systems

    • The Vertebrate Spinal Cord

    • The Vertebrate Brain

    • The Olfactory and Visual Sensory Systems

    • LIM-HD Genes and Early Patterning Events in the Developing CNS

  • Factors that Interact with LIM-HD Proteins

  • Downstream Targets of LIM-HD Proteins

  • Conclusion and Future Directions

  • Abbreviations