Chapter 1. Lipid Rafts, Caveolae, and Membrane Traffic

  1. Prof. Dr. Christopher J. Fielding2,3
  1. Doris Meder,
  2. Kai Simons

Published Online: 6 JUN 2006

DOI: 10.1002/3527608079.ch1

Lipid Rafts and Caveolae: From Membrane Biophysics to Cell Biology

Lipid Rafts and Caveolae: From Membrane Biophysics to Cell Biology

How to Cite

Meder, D. and Simons, K. (2006) Lipid Rafts, Caveolae, and Membrane Traffic, in Lipid Rafts and Caveolae: From Membrane Biophysics to Cell Biology (ed C. J. Fielding), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, FRG. doi: 10.1002/3527608079.ch1

Editor Information

  1. 2

    Cardiovascular Research Institute and Department of Medicine, University of California San Francisco, San Francisco, CA 94143, USA

  2. 3

    Cardiovascular Research Institute and Department of Physiology, University of California San Francisco, San Francisco, CA 94143, USA

Author Information

  1. Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstr. 108, 01307 Dresden, Germany

Publication History

  1. Published Online: 6 JUN 2006
  2. Published Print: 9 JAN 2006

ISBN Information

Print ISBN: 9783527312610

Online ISBN: 9783527608072

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Keywords:

  • lipid rafts;
  • caveolae;
  • membrane traffic;
  • cell membrane;
  • basic organization principles of a cell membrane;
  • evidence for phase separation in cell membranes

Summary

This chapter contains sections titled:

  • Introduction

  • Basic Organization Principles of a Cell Membrane

  • Evidence for Phase Separation in Model Membrane Systems: Liquid-Ordered and Liquid-Disordered Phases

  • Evidence for Phase Separation in Cell Membranes: The “Raft Concept”

  • Raft Domains are Clustered to Exert their Function

  • The Apical Membrane of Epithelial Cells: A Percolating Raft Membrane at 25 °C

  • Caveolae: Scaffolded Membrane Domains Rich in Raft Lipids

  • Caveolae and Lipid Rafts in Membrane Traffic