Chapter 10. Thyroid Cancer

  1. David Machin3,4,5,
  2. Simon Day6 and
  3. Sylvan Green7
  1. Vijayaraman Arutchelvam1 and
  2. Petros Perros2

Published Online: 17 MAY 2007

DOI: 10.1002/9780470010167.ch10

Textbook of Clinical Trials, Second Edition

Textbook of Clinical Trials, Second Edition

How to Cite

Arutchelvam, V. and Perros, P. (2006) Thyroid Cancer, in Textbook of Clinical Trials, Second Edition (eds D. Machin, S. Day and S. Green), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470010167.ch10

Editor Information

  1. 3

    Division of Clinical Trials and Epidemiological Sciences, National Cancer Centre Singapore, 11 Hospital Drive, Singapore 16910, Singapore

  2. 4

    UK Children's Cancer Study Group, University of Leicester, UK

  3. 5

    Medical Statistics Group, School of Health and Related Sciences, University of Sheffield, UK

  4. 6

    Licensing Division, Medicines and Healthcare products Regulatory Agency, Room 13–205 Market Towers, 1 Nine Elms Lane, London SW8 5NQ, UK

  5. 7

    Arizona Cancer Centre, Tucson, Arizona, USA

Author Information

  1. 1

    97 Darras Road, Darras Hall, Ponteland, Newcastle upon Tyne NE20 9PQ, UK

  2. 2

    Endocrine Unit, Freeman Hospital, Freeman Road, Newcastle upon Tyne NE7 7DN, UK

Publication History

  1. Published Online: 17 MAY 2007
  2. Published Print: 24 NOV 2006

ISBN Information

Print ISBN: 9780470010143

Online ISBN: 9780470010167



  • thyroid cancer - commonest endocrine malignancy;
  • tumour staging and prognostic scoring;
  • thyroid surgery;
  • suppressive thyroxine therapy;
  • rhTSH therapeutic use


This chapter contains sections titled:

  • Introduction

  • Tumour Staging and Prognostic Scoring

  • Thyroid Surgery

  • Post-Operative 131I Ablation

  • Suppressive Thyroxine Therapy

  • Diagnostic Use of Recombinant Human TSH (rhTSH)

  • Therapeutic Use of rhTSH

  • Fluorine-18 Fluorodeoxyglucose (FDG) Positron Emission Tomography (PET) Scanning

  • Conclusion

  • References