Chapter 14. Cardiovascular Disease

  1. David Machin2,3,4,
  2. Simon Day5 and
  3. Sylvan Green6
  1. Krishna Prasad

Published Online: 17 MAY 2007

DOI: 10.1002/9780470010167.ch14

Textbook of Clinical Trials, Second Edition

Textbook of Clinical Trials, Second Edition

How to Cite

Prasad, K. (2006) Cardiovascular Disease, in Textbook of Clinical Trials, Second Edition (eds D. Machin, S. Day and S. Green), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470010167.ch14

Editor Information

  1. 2

    Division of Clinical Trials and Epidemiological Sciences, National Cancer Centre Singapore, 11 Hospital Drive, Singapore 16910, Singapore

  2. 3

    UK Children's Cancer Study Group, University of Leicester, UK

  3. 4

    Medical Statistics Group, School of Health and Related Sciences, University of Sheffield, UK

  4. 5

    Licensing Division, Medicines and Healthcare products Regulatory Agency, Room 13–205 Market Towers, 1 Nine Elms Lane, London SW8 5NQ, UK

  5. 6

    Arizona Cancer Centre, Tucson, Arizona, USA

Author Information

  1. Licensing Division, Medicines and Healthcare products Regulatory Agency, 1 Market Towers, Nine Elms Lane, London SW8 5NQ, UK

Publication History

  1. Published Online: 17 MAY 2007
  2. Published Print: 24 NOV 2006

ISBN Information

Print ISBN: 9780470010143

Online ISBN: 9780470010167

SEARCH

Keywords:

  • cardiovascular disease;
  • genotype/phenotype interactions;
  • placebo or active control;
  • antiarrhythmic agent trials;
  • DASH (Dietary Approaches to Stop Hypertension)

Summary

This chapter contains sections titled:

  • Introduction

  • Facts to Consider in Cardiovascular Clinical Trials

  • Phase I and Phase II Trials

  • Pharmacological Agents/Interventions

  • Trials Involving Devices or Surgical Procedures

  • Trials of Behavioural Change

  • Trials of ‘Nurse-Led Intervention’

  • Summary

  • References