Chapter 3. The Cochrane Collaboration

  1. David Machin2,3,4,
  2. Simon Day5 and
  3. Sylvan Green6
  1. Mike Clarke

Published Online: 17 MAY 2007

DOI: 10.1002/9780470010167.ch3

Textbook of Clinical Trials, Second Edition

Textbook of Clinical Trials, Second Edition

How to Cite

Clarke, M. (2006) The Cochrane Collaboration, in Textbook of Clinical Trials, Second Edition (eds D. Machin, S. Day and S. Green), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470010167.ch3

Editor Information

  1. 2

    Division of Clinical Trials and Epidemiological Sciences, National Cancer Centre Singapore, 11 Hospital Drive, Singapore 16910, Singapore

  2. 3

    UK Children's Cancer Study Group, University of Leicester, UK

  3. 4

    Medical Statistics Group, School of Health and Related Sciences, University of Sheffield, UK

  4. 5

    Licensing Division, Medicines and Healthcare products Regulatory Agency, Room 13–205 Market Towers, 1 Nine Elms Lane, London SW8 5NQ, UK

  5. 6

    Arizona Cancer Centre, Tucson, Arizona, USA

Author Information

  1. UK Cochrane Centre, NHS R&D Programme, Summertown Pavilion, Middle Way, Oxford OX2 7LG, UK

Publication History

  1. Published Online: 17 MAY 2007
  2. Published Print: 24 NOV 2006

ISBN Information

Print ISBN: 9780470010143

Online ISBN: 9780470010167



  • Cochrane collaboration and health care;
  • Cochrane collaboration and systematic reviews;
  • Cochrane collaboration structure;
  • Cochrane reviews underway;
  • Cochrane Central Register of Controlled Trials (CENTRAL)


This chapter contains sections titled:

  • Introduction

  • The Need for Systematic Reviews

  • The Conduct of Systematic Reviews

  • Systematic Reviews and the Cochrane Collaboration

  • History of the Cochrane Collaboration

  • Structure of the Cochrane Collaboration

  • Accessibility of Cochrane Reviews

  • Other Output From the Cochrane Collaboration

  • Conclusions

  • References