Chapter 6. Gastrointestinal Cancers

  1. David Machin3,4,5,
  2. Simon Day6 and
  3. Sylvan Green7
  1. Daniel Sargent1,
  2. Richard Goldberg2 and
  3. Paul Limburg1

Published Online: 17 MAY 2007

DOI: 10.1002/9780470010167.ch6

Textbook of Clinical Trials, Second Edition

Textbook of Clinical Trials, Second Edition

How to Cite

Sargent, D., Goldberg, R. and Limburg, P. (2006) Gastrointestinal Cancers, in Textbook of Clinical Trials, Second Edition (eds D. Machin, S. Day and S. Green), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470010167.ch6

Editor Information

  1. 3

    Division of Clinical Trials and Epidemiological Sciences, National Cancer Centre Singapore, 11 Hospital Drive, Singapore 16910, Singapore

  2. 4

    UK Children's Cancer Study Group, University of Leicester, UK

  3. 5

    Medical Statistics Group, School of Health and Related Sciences, University of Sheffield, UK

  4. 6

    Licensing Division, Medicines and Healthcare products Regulatory Agency, Room 13–205 Market Towers, 1 Nine Elms Lane, London SW8 5NQ, UK

  5. 7

    Arizona Cancer Centre, Tucson, Arizona, USA

Author Information

  1. 1

    Gastroenterology and Hepatology, Mayo Clinic, 200 1st Street, SW, Kahler 1A, Rochester, MN 55905, USA

  2. 2

    Division of Hematology/Oncology, The University of North Carolina at Chapel Hill, CB# 7305, 3009 Old Clinic Bldg, Chapel Hill, NC 27599-7305, USA

Publication History

  1. Published Online: 17 MAY 2007
  2. Published Print: 24 NOV 2006

ISBN Information

Print ISBN: 9780470010143

Online ISBN: 9780470010167



  • gastrointestinal cancers;
  • oesophageal and gastric cancer;
  • pancreatic cancer;
  • cancer chemoprevention;
  • theoretical surgical approach of total mesorectal excision (TME)


This chapter contains sections titled:

  • Introduction

  • Oesophageal Cancer

  • Gastric Cancer

  • Pancreatic Cancer

  • Colorectal Cancer

  • Case Study: 5-Fu Plus Leucovorin in Colon Cancer

  • References