Protein Synthesis Initiation in Bacteria
Published Online: 21 DEC 2007
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Grunberg-Manago, M., Studer, S. M. and Joseph, S. 2007. Protein Synthesis Initiation in Bacteria. eLS. .
- Published Online: 21 DEC 2007
This is not the most recent version of the article. View current version (15 AUG 2014)
Translation initiation begins with the assembly of the pre-initiation complex followed by the formation of the initiation complex. The process of initiation then continues until the first peptide bond is formed; it is at this point that translation begins. The formation of the pre-initiation/initiation complex is often the rate-limiting step during the process of translation, as it is influenced by a number of translational regulatory mechanisms. As a result, the process of initiation can play a significant role in gene expression.
- initiation factors;
- Shine–Dalgarno sequence