Enzymatic Rate Enhancements
Published Online: 21 DEC 2007
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Quinn, D. M. and Sikorski, R. S. 2007. Enzymatic Rate Enhancements. eLS. .
- Published Online: 21 DEC 2007
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Enzymatic rate enhancements arise from the unmatched ability of enzymes to stabilize the transition states of the reactions that they catalyse. The purpose of this article is to discuss the magnitude and mechanistic origins of enzymatic rate enhancements. Selected enzymes are described that manifest a wide range of rate enhancements and corresponding catalytic strategies.
- catalytic acceleration;
- transition state stabilization;
- diffusion control;
- enzyme mechanisms;
- enzyme catalysis