Standard Article

Regulatory Systems: Two-component

  1. Tracy L Raivio

Published Online: 15 SEP 2006

DOI: 10.1002/9780470015902.a0000856.pub2



How to Cite

Raivio, T. L. 2006. Regulatory Systems: Two-component. eLS. .

Author Information

  1. University of Alberta, Alberta, Canada

Publication History

  1. Published Online: 15 SEP 2006


Two-component systems constitute a large class of regulatory proteins that function as signal transducers. Each system comprises a sensor or histidine kinase and an effector or response regulator, which communicate through a conserved set of phosphotransfer reactions to effect adaptive changes in response to specific environmental signals.


  • two-component;
  • histidine kinase;
  • response regulator;
  • signal transduction