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RNA Interactions in mRNA Splicing

  1. Andrew J Newman

Published Online: 14 MAR 2008

DOI: 10.1002/9780470015902.a0000881.pub2

eLS

eLS

How to Cite

Newman, A. J. 2008. RNA Interactions in mRNA Splicing. eLS. .

Author Information

  1. MRC Laboratory of Molecular Biology, Cambridge, UK

Publication History

  1. Published Online: 14 MAR 2008

Abstract

Complex ribonucleoprotein machines called spliceosomes remove introns from nuclear messenger ribonucleic acid (mRNA) precursors by mRNA splicing. A dynamic network of RNA interactions in the spliceosome plays crucial roles in splice site recognition and provides a structural framework for the catalytic steps of mRNA splicing.

Keywords:

  • splicing;
  • mRNA;
  • spliceosome;
  • snRNA