Standard Article

Immunological Accessory Molecules

  1. Stephen H Benedict1,
  2. Kelli M Cool1,
  3. Abby L Dotson1,
  4. Marcia A Chan2

Published Online: 21 DEC 2007

DOI: 10.1002/9780470015902.a0000923.pub2



How to Cite

Benedict, S. H., Cool, K. M., Dotson, A. L. and Chan, M. A. 2007. Immunological Accessory Molecules. eLS. .

Author Information

  1. 1

    University of Kansas, Lawrence, Kansas, USA

  2. 2

    Children's Mercy Hospital, Kansas City, Missouri, USA

Publication History

  1. Published Online: 21 DEC 2007


Immunological accessory molecules are proteins expressed on the surface of immune cells that can modulate in a positive or negative manner the ability of the cell to develop or to perform one or more of its functions. Thus, accessory molecules are critical to the success or failure of controlling the immune response to foreign antigens such as infectious agents or organ transplants, the aberrant response to self-antigens as in the case of autoimmune disease or the response to tumours.


  • adhesion molecules;
  • Fc receptors;
  • tetraspanins;
  • cytokine;
  • chemokine;
  • pattern recognition