Standard Article

Genetic Networks

  1. James A Coffman1,
  2. Eric H Davidson2

Published Online: 28 SEP 2007

DOI: 10.1002/9780470015902.a0001170.pub2



How to Cite

Coffman, J. A. and Davidson, E. H. 2007. Genetic Networks. eLS. .

Author Information

  1. 1

    Mount Desert Island Biological Laboratory, Maine, USA

  2. 2

    California Institute of Technology, Pasadena, California, USA

Publication History

  1. Published Online: 28 SEP 2007


Gene expression is regulated by sequence-specific protein–DNA (deoxyribonucleic acid) interactions that occur within the cis-regulatory domains of genes. Genes that encode sequence-specific DNA-binding proteins both regulate and are regulated by the expression of other such genes. A set of genes whose activity is thus linked by sequence-specific cis-trans regulatory interactions constitutes a genetic network.


  • transcription;
  • cis-regulatory;
  • DNA-binding;
  • information processing;
  • genome;
  • development