Standard Article

Haematopoietic Growth Factors

  1. Daniel Thomas,
  2. Angel F Lopez

Published Online: 15 MAR 2009

DOI: 10.1002/9780470015902.a0001287.pub2

eLS

eLS

How to Cite

Thomas, D. and Lopez, A. F. 2009. Haematopoietic Growth Factors. eLS. .

Author Information

  1. Cytokine Receptor Laboratory, Hanson Institute, Adelaide, Australia

Publication History

  1. Published Online: 15 MAR 2009

This is not the most recent version of the article. View current version (15 JUL 2015)

Abstract

Haematopoietic growth factors regulate the production of all the cellular elements of blood by stimulating the proliferation, survival and differentiation of haematopoietic cells in various stages of maturation and also enhancing certain mature cell functions. Recombinant growth factors are used in the clinic to stimulate cell production as part of treatment for anaemia, neutropenia and thrombocytopenia and to aid in the collection of bone marrow stem cells.

Keywords:

  • cytokine;
  • haematopoiesis;
  • receptor;
  • colony-stimulating factor;
  • signal transduction