Protein–DNA Complexes: Nonspecific
Published Online: 28 SEP 2007
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Saecker, R. M. 2007. Protein–DNA Complexes: Nonspecific. eLS.
- Published Online: 28 SEP 2007
Nonspecific protein–DNA complexes form largely independently of deoxyribonucleic acid (DNA) sequence or structure. Typically, the thermodynamic driving force for forming these complexes is electrostatic due to the polyelectrolyte (polyanionic) nature of the DNA.
- nonspecific binding;
- protein–nucleic interactions;
- polyelectrolyte effect