Ion Motive ATPases: P-type ATPases
Published Online: 15 SEP 2009
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Shin, J. M. and Sachs, G. 2009. Ion Motive ATPases: P-type ATPases. eLS. .
- Published Online: 15 SEP 2009
Regulation of ions such as calcium, sodium and potassium ions is very important for cell life. One of ion-regulating enzymes is classified as ion motive adenosine triphosphatase (ATPase). Ion motive ATPases exchange two different ions across the membrane at the expense of ATP energy. The Ca2+-ATPase transports Ca ion in exchange for H ion; the Na+/K+ or H+/K+ ATPase transports Na ion or hydronium ion from the cytoplasmic region to the exocytoplasmic region with the exchange of K ion from the exoplasmic domain to the cytoplasmic domain. The Ca2+-ATPase has single catalytic subunit. The Na+/K+ and H+/K+ ATPases consist of two subunits α and β. The α subunit is the catalytic subunit, having 10 transmembrane domains. The β subunit is a glycosylated protein.
Ion motive ATPases
P-type ATPase transport ions across the membrane
Regulating ion concentrations.