Published Online: 21 DEC 2007
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Moore, C. M. and Best, R. G. 2007. Chromosome Mechanics. eLS.
- Published Online: 21 DEC 2007
Chromosome mechanics describes the processes of chromosome replication and behaviour as they relate to somatic cell division and gametogenesis. Mitosis produces identical diploid somatic cells, whereas meiosis produces haploid germ cells with recombination of parental alleles. Aberrations occur in these processes that include chromosomal nondisjunction leading to numerical abnormalities and unrepaired deoxyribonucleic acid (DNA) damage resulting in chromosomal breakage and structural rearrangements.