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Chromosome Mechanics

  1. Charleen M Moore1,
  2. Robert G Best2

Published Online: 21 DEC 2007

DOI: 10.1002/9780470015902.a0001441.pub2

eLS

eLS

How to Cite

Moore, C. M. and Best, R. G. 2007. Chromosome Mechanics. eLS. .

Author Information

  1. 1

    University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA

  2. 2

    University of South Carolina School of Medicine, Columbia, South Carolina, USA

Publication History

  1. Published Online: 21 DEC 2007

Abstract

Chromosome mechanics describes the processes of chromosome replication and behaviour as they relate to somatic cell division and gametogenesis. Mitosis produces identical diploid somatic cells, whereas meiosis produces haploid germ cells with recombination of parental alleles. Aberrations occur in these processes that include chromosomal nondisjunction leading to numerical abnormalities and unrepaired deoxyribonucleic acid (DNA) damage resulting in chromosomal breakage and structural rearrangements.

Keywords:

  • mitosis;
  • meiosis;
  • recombination;
  • nondisjunction;
  • spermatogenesis;
  • oogenesis