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Gene Expression: Frameshifting

  1. John F Atkins1,2,
  2. Raymond F Gesteland1

Published Online: 16 APR 2007

DOI: 10.1002/9780470015902.a0001498.pub2



How to Cite

Atkins, J. F. and Gesteland, R. F. 2007. Gene Expression: Frameshifting. eLS. .

Author Information

  1. 1

    University of Utah, Salt Lake City, Utah, USA

  2. 2

    University College Cork, Cork, Ireland

Publication History

  1. Published Online: 16 APR 2007


Ribosomes shift reading frames at high levels at specific places in the decoding of a minority of messenger ribonucleic acid (RNA)s in probably all organisms. This frameshifting serves a regulatory function or is used to synthesize more than one product from a coding sequence.


  • genetic code;
  • frameshift;
  • recoding;
  • ribosomes