Multigene Families: Evolution
Published Online: 30 APR 2008
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Walsh, J. B. and Stephan, W. 2008. Multigene Families: Evolution. eLS.
- Published Online: 30 APR 2008
Groups of genes showing similarity with each other are referred to as a gene family, arising from wholesale or partial gene duplication. The clustering of functionally related members of a gene family reflects their common ancestry and subsequent duplication and divergence. It has been speculated that gene duplication is essential for the creation of major evolutionary novelty. Genome projects will help in understanding the importance of gene duplications underlying macroevolutionary events.
Keywords: paralogous genes; orthologous genes; pseudogenes; processed pseudogenes; concerted evolution