Published Online: 15 JUL 2008
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Yampolsky, L. Y. and Stoltzfus, A. 2008. Mutational Biases. eLS. .
- Published Online: 15 JUL 2008
Mutational biases refer to systematic asymmetries or nonuniformities in the occurrence of mutations, heritable changes that take place in an individual organism. Mutational biases arise by asymmetries in damage, repair and replication of the genetic material. Many such biases are known: familiar examples include transition:transversion bias, the CpG effect and deletion:insertion bias. Mutation biases are biologically significant to the extent that they modulate the probabilities of heritable diseases and of evolutionary changes.
- transition–transversion bias;
- GC bias;
- strand-specific bias;
- insertion–deletion bias