Chronic Lymphocytic Leukaemia
Published Online: 28 SEP 2007
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Dearden, C. 2007. Chronic Lymphocytic Leukaemia. eLS. .
- Published Online: 28 SEP 2007
This is not the most recent version of the article. View current version (15 JAN 2013)
Chronic lymphocytic leukaemia (CLL) results from the expansion of a clone of CD5+ B lymphocytes with distinct morphology and membrane antigens. The clinical course is variable and is determined by the stage of the disease. Genetic abnormalities detected by fluorescence in situ hybridization (FISH) analysis are important determinants of prognosis. Treatment is only indicated in symptomatic patients with active disease.
- B lymphocytes;
- lymphocytic leukaemia;
- clinical stage;
- doubling time;