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Cerebrospinal Fluid and its Abnormalities

  1. Michael Chan,
  2. Sepideh Amin-Hanjani

Published Online: 15 JAN 2010

DOI: 10.1002/9780470015902.a0002191.pub2



How to Cite

Chan, M. and Amin-Hanjani, S. 2010. Cerebrospinal Fluid and its Abnormalities. eLS. .

Author Information

  1. University of Illinois at Chicago, Chicago, USA

Publication History

  1. Published Online: 15 JAN 2010
Table 1. Composition of CSF and plasma in humans
ConstituentMean CSF concentrationMean plasma concentration
  1. Source: Adapted from Fishman 1992.

Osmolarity295 mOsm L−1295 mOsm L−1
Sodium138.0 mEq L−1138.0 mEq L−1
Potassium2.8 mEq L−14.5 mEq L−1
Calcium2.1 mEq L−14.8 mEq L−1
Magnesium2.3 mEq L−11.7 mEq L−1
Chloride119.0 mEq L−1102.0 mEq L−1
Bicarbonate22.0 mEq L−124.0 mEq L−1
Glucose60.0 mg dL−190.0 mg dL−1
Lactate1.6 mEq L−11.0 mEq L−1
Creatinine1.2 mg dL−11.8 mg dL−1
Total lipid1.5 mg dL−1750.0 mg dL−1
Total protein35.0 mg dL−17000 mg dL−1
Table 2. Aetiology of hydrocephalus in 170 paediatric patients
  1. Source: Adapted from Amacher and Wellington 1984.

Congenital113 (66.5%)
Perinatal haemorrhage18 (10.6%)
Tumour18 (10.6%)
Infection13 (7.6%)
Trauma/subarachnoid haemorrhage8 (4.7%)