Epitope Mapping: B-cell Epitopes
Published Online: 28 SEP 2007
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Morris, G. 2007. Epitope Mapping: B-cell Epitopes. eLS. .
- Published Online: 28 SEP 2007
Immunoglobulin molecules are folded to present a surface structure complementary to a surface feature on the antigen – the epitope is this feature of the antigen. Epitope mapping is the process of locating the antibody-binding site on the antigen, although the term is also applied more broadly to receptor–ligand interactions unrelated to the immune system.
- phage display;
- mass spectrometry;
- site-directed mutagenesis;