Posttranslational Processing: Peptide Hormones and Neuropeptide Transmitters
Published Online: 21 DEC 2007
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Varro, A. 2007. Posttranslational Processing: Peptide Hormones and Neuropeptide Transmitters. eLS. .
- Published Online: 21 DEC 2007
The regulatory peptides that act as hormones, paracrine messengers or neurotransmitters are generally synthesized initially as large, inactive precursors that are converted to their active forms by a variety of different posttranslational processing steps including cleavage of the peptide chain and modification to individual residues for example by sulfation, phosphorylation, glycosylation and COOH-terminal amidation.
- regulatory peptides;
- prohormone convertases;
- secretory pathway