T Lymphocytes: Regulatory
Published Online: 15 DEC 2008
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Fehervari, Z. and Sakaguchi, S. 2008. T Lymphocytes: Regulatory. eLS. .
- Published Online: 15 DEC 2008
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CD4+ regulatory (Treg) T cells play a central role in the immune system by potently controlling the responses of other immunocytes. Their activity appears to be essential not only for the maintenance of immunological self-tolerance but potentially also for the control of all physiological immune responses whether against normal self-proteins, microbes or cancerous cells. A fuller understanding of these cells should allow us to effectively exploit their suppressive functions for clinical benefit.
- CD25+CD4+T cell;
- regulatory T cell;