Insertion and Deletion of Exons during Human Gene Evolution
Published Online: 28 SEP 2007
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Cooper, D. N. 2007. Insertion and Deletion of Exons during Human Gene Evolution. eLS. .
- Published Online: 28 SEP 2007
During the evolution of human genes, exons have been both acquired and lost. The study of the structure of orthologous mammalian genes provides numerous examples of the gain or loss of exons by a variety of different mechanisms.
- exon deletion;
- exon insertion;
- exon duplication/amplification;
- exon shuffling;
- LINE element-mediated recombination;
- alternative splicing;