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Gene Fusion

  1. Esther Betrán

Published Online: 14 MAR 2008

DOI: 10.1002/9780470015902.a0005099.pub2



How to Cite

Betrán, E. 2008. Gene Fusion. eLS. .

Author Information

  1. University of Texas, Arlington, Texas, USA

Publication History

  1. Published Online: 14 MAR 2008

This is not the most recent version of the article. View current version (15 MAY 2013)


Gene fusion is a process by which the whole or parts of two or more distinct genes are juxtaposed and fused into a single gene. Often, a new gene and function can originate in this way. This phenomenon has been broadly observed in organisms ranging from higher eukaryotes to prokaryotes. Recent gene fusions reveal the mechanisms behind this phenomenon. Genome studies reveal the high and incessant incidence of gene fusions in genome evolution.


  • exon shuffling;
  • gene fusion;
  • illegitimate recombination;
  • retroposition;
  • new gene origination