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Major Histocompatibility Complex (MHC) Genes: Evolution

  1. Austin L Hughes

Published Online: 30 APR 2008

DOI: 10.1002/9780470015902.a0005133.pub2



How to Cite

Hughes, A. L. 2008. Major Histocompatibility Complex (MHC) Genes: Evolution. eLS. .

Author Information

  1. University of South Carolina, Columbia, South Carolina, USA

Publication History

  1. Published Online: 30 APR 2008


The major histocompatibility complex is a family of genes whose products play a key role in the immune system, presenting peptides to T cells. This family includes the most polymorphic loci known in animals.


  • human leukocyte antigen;
  • immune system genes;
  • major histocompatibility complex;
  • multigene families;
  • polymorphism