Published Online: 14 MAR 2008
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Altschul, S. F. 2008. Substitution Matrices. eLS. .
- Published Online: 14 MAR 2008
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A substitution matrix is a collection of scores for aligning nucleotides or amino acids with one another. These scores generally represent the relative ease with which one nucleotide or amino acid may mutate into or substitute for another, and they are used to measure similarity in sequence alignments.
- alignment score;
- sequence similarity;
- gap costs;
- PAM matrices;
- BLOSUM matrices