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Transcription Factors

  1. David S Latchman

Published Online: 28 SEP 2007

DOI: 10.1002/9780470015902.a0005278.pub2

eLS

eLS

How to Cite

Latchman, D. S. 2007. Transcription Factors. eLS. .

Author Information

  1. University of London, Birkbeck College, London, UK

Publication History

  1. Published Online: 28 SEP 2007

Abstract

Transcription factors are regulatory proteins that can increase or decrease the transcription of a particular gene from deoxyribonucleic acid into the corresponding ribonucleic acid. They play a key role in embryonic development, the creation and maintenance of cell type- and tissue-specific patterns of protein synthesis and the response to cellular signalling pathways.

Keywords:

  • DNA binding;
  • transcriptional activation;
  • transcriptional repression;
  • cellular signalling;
  • human disease