Tissue-specific Locus Control: Structure and Function
Published Online: 28 SEP 2007
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Bonifer, C. 2007. Tissue-specific Locus Control: Structure and Function. eLS. .
- Published Online: 28 SEP 2007
All developmental processes involve decisions in which the developmental fate of precursor cells is restricted to a single lineage by establishing a unique gene expression pattern. The activation at each of these gene loci involves restructuring chromatin as a necessary prerequisite for the assembly of the transcription apparatus. Tissue-specific locus activation is controlled by the interplay between sequence-specific transcription factors, chromatin-modifying activities and basic chromatin components.
- gene locus activation;
- transcriptional control elements;
- position effect;