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Gene Structure: Evolution

  1. Tomoko Ohta

Published Online: 14 MAR 2008

DOI: 10.1002/9780470015902.a0005301.pub2



How to Cite

Ohta, T. 2008. Gene Structure: Evolution. eLS. .

Author Information

  1. National Institute of Genetics, Mishima, Japan

Publication History

  1. Published Online: 14 MAR 2008

This is not the most recent version of the article. View current version (15 APR 2013)


Two fundamental processes in the evolution of gene structure in populations are the production of variations by mutations and the natural selection that filters these variations. Mutations occur randomly in genomes of germ cell lineages and are rejected or selected for, so that genes perform needed functions. As a result of minute effects of most mutations, both genetic drift and natural selection influence their fate in a population.


  • nucleotide substitution;
  • gene duplication;
  • natural selection;
  • random genetic drift