Long Interspersed Nuclear Elements (LINEs): Evolution
Published Online: 15 JUL 2008
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Furano, A. V. and Boissinot, S. 2008. Long Interspersed Nuclear Elements (LINEs): Evolution. eLS. .
- Published Online: 15 JUL 2008
LINE-1 (long interspersed nuclear element-1, L1) repeated deoxyribonucleic acid (DNA) elements are non-long terminal repeat (LTR) group of retrotransposons that replicate by copying (reverse transcribing) their ribonucleic acid (RNA) transcript into genomic DNA. LINE-1 elements, which can also copy other RNAs into genomic DNA, are the dominant (and in some species the only) active clade of retrotransposons in mammals, where they have been replicating and evolving since before the mammalian radiation approximately 100 million years ago.