Published Online: 15 JUL 2008
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Heringa, J. 2008. Sequence Similarity. eLS. .
- Published Online: 15 JUL 2008
Sequence similarity is a measure of an empirical relationship between sequences. A common objective of sequence similarity calculations is establishing the likelihood for sequence homology: the chance that sequences have evolved from a common ancestor. A similarity score is therefore aimed to approximate the evolutionary distance between a pair of nucleotide or protein sequences. Many implementations for measuring sequence similarity exist, where a general aim is to infer structural or functional characteristics of an unannotated molecular sequence.
- sequence similarity;
- sequence identity;
- homology searching;