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Fragile Sites

  1. Grant R Sutherland

Published Online: 16 APR 2007

DOI: 10.1002/9780470015902.a0005547.pub2



How to Cite

Sutherland, G. R. 2007. Fragile Sites. eLS. .

Author Information

  1. Women's and Children's Hospital, Adelaide, Australia

Publication History

  1. Published Online: 16 APR 2007


Fragile sites are specific points on chromosomes that show nonrandom gaps or breaks when the cells from which the chromosomes have been prepared have been exposed to a specific chemical agent or condition of tissue culture. Hence a fragile site is an area of chromatin which is not compacted when viewed in mitosis.


  • fragile X syndrome;
  • Jacobsen syndrome;
  • trinucleotide repeat;
  • fragile site;
  • FRAXA;