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Dolly and Polly

  1. Alan Petersen

Published Online: 15 SEP 2006

DOI: 10.1002/9780470015902.a0005598



How to Cite

Petersen, A. 2006. Dolly and Polly. eLS. .

Author Information

  1. University of Plymouth, Plymouth, UK

Publication History

  1. Published Online: 15 SEP 2006


Dolly, born in 1996, achieved notoriety by being the first mammal to be cloned from the nucleus of a fully differentiated cell, taken from the udder of an adult sheep. Polly, born a year after Dolly, was not only cloned but was also genetically transformed; that is, she carried an introduced gene that codes the protein factor IX, which is involved in blood clotting, which has huge therapeutic value.


  • Dolly;
  • Polly;
  • cloning;
  • pharming;
  • nuclear transfer;
  • reproductive cloning;
  • therapeutic cloning