Mammalian Sex Chromosome Evolution
Published Online: 15 JUL 2008
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Wyckoff, G. J. and Malcom, C. M. 2008. Mammalian Sex Chromosome Evolution. eLS.
- Published Online: 15 JUL 2008
Although they are highly dissimilar in sequence content in extant organisms, the mammalian sex chromosomes (i.e. the X and Y) evolved from a pair of autosomes. Differentiation of the sex chromosomes during evolution was initiated by the suppression of XY recombination. This was followed by the general degeneration of genes on the Y-chromosome, with specific instances of gene specialization on the nonrecombining portion of the Y.
Keywords: X-chromosome; Y-chromosome; mammalian sex chromosomes; Y degeneration; pseudoautosomal region; nonrecombining Y