Chromosomal Rearrangements in Primates
Published Online: 15 JUL 2008
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Stanyon, R. and Bigoni, F. 2008. Chromosomal Rearrangements in Primates. eLS. .
- Published Online: 15 JUL 2008
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Comparative molecular cytogenetics techniques allow us to trace the chromosome rearrangements which have occurred during primate and human evolution. Technique such as fluorescence in situ hybridization (FISH) of whole chromosome paints (WCP) allows us to track interchromosomal rearrangements (translocations). FISH with smaller probes such as bacterial artificial chromosomes (BAC) allows us to study intrachromosomal rearrangements such as inversions. These data show that human chromosomes are amazingly similar to those of great apes and most Old World monkeys. Human chromosomes can be derived from the ancestral primate karyotype by a limited number of rearrangements.
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