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Chromosome 8

  1. Matthew J Hilton1,
  2. Dan E Wells2

Published Online: 16 APR 2007

DOI: 10.1002/9780470015902.a0005817.pub2

eLS

eLS

How to Cite

Hilton, M. J. and Wells, D. E. 2007. Chromosome 8. eLS. .

Author Information

  1. 1

    Washington University School of Medicine, St. Louis, Missouri, USA

  2. 2

    University of Houston, Houston, Texas, USA

Publication History

  1. Published Online: 16 APR 2007

Abstract

Chromosome 8 is a submetacentric chromosome containing about 5% of the euchromatic human genome that is associated with approximately 96 diseases or syndromes. Notably, it contains a region of strikingly high mutation rate in which the majority of the genes are involved in development or signalling of the nervous system.

Keywords:

  • chromosome 8;
  • syndrome;
  • disease genes;
  • sequencing