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Serine Proteases

  1. Michael J Page,
  2. Enrico Di Cera

Published Online: 28 SEP 2007

DOI: 10.1002/9780470015902.a0005902.pub2



How to Cite

Page, M. J. and Cera, E. D. 2007. Serine Proteases. eLS. .

Author Information

  1. Washington University School of Medicine, St. Louis, Missouri, USA

Publication History

  1. Published Online: 28 SEP 2007


Serine proteases are enzymes that utilize a nucleophilic hydroxyl group donated from a serine amino acid side-chain to hydrolyse the peptide bond of a substrate. Serine proteases mediate diverse biological processes from nonspecific digestion to highly regulated specific protein processing.


  • enzyme;
  • catalysis;
  • proteolysis;
  • protease;
  • peptidase