Standard Article


  1. Ravi Shridhar1,
  2. Daniel Keppler2,
  3. Bonnie F Sloane1

Published Online: 15 SEP 2006

DOI: 10.1002/9780470015902.a0005904



How to Cite

Shridhar, R., Keppler, D. and Sloane, B. F. 2006. Cystatins. eLS. .

Author Information

  1. 1

    Wayne State University, Detroit, Michigan, USA

  2. 2

    Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA

Publication History

  1. Published Online: 15 SEP 2006


Cystatins are endogenous inhibitors of papain-like cysteine proteases. Since the discovery that a polypeptide from chicken egg-whites (chicken cystatin) could inhibit the plant cysteine protease, papain, more than 40 mammalian cystatins have been isolated.


  • cystatins;
  • stefins;
  • kininogens;
  • cathepsins;
  • cysteine protease inhibitors