Cytogenetic and Physical Chromosomal Maps: Integration
Published Online: 15 SEP 2006
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Kirsch, I. R. and Ried, T. 2006. Cytogenetic and Physical Chromosomal Maps: Integration. eLS. .
- Published Online: 15 SEP 2006
It is now possible to link a cytogenetic location directly with the sequence of the human genome. This is accomplished by using a toolset consisting of high-resolution fluorescent in situ hybridization-mapped and sequenced bacterial artificial chromosome clones distributed at 1–2 Mb intervals across the genome. This toolset is available from a commercial repository and is searchable in publicly available databases cross-referenced to extant information on cancer-associated chromosomal aberrations.
- bacterial artificial chromosomes;
- fluorescent in situ hybridization;
- genome sequence;