Clustering of Highly Expressed Genes in the Human Genome
Published Online: 30 APR 2008
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Gierman, H. J. and Versteeg, R. 2008. Clustering of Highly Expressed Genes in the Human Genome. eLS. .
- Published Online: 30 APR 2008
A dual mechanism of gene regulation exists in the human genome: Transcription factors determine whether a gene will be expressed and establish a basic level of transcription. In addition, the chromosomal domain in which a gene is positioned exerts a substantial effect and potentiates the ultimate expression level.
- chromosomal domains;
- gene expression;
- genome organization;
- gene clustering