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Oxidative Phosphorylation System: Nuclear Genes and Genetic Disease

  1. Leo Nijtmans,
  2. Lambert van den Heuvel,
  3. Jan AM Smeitink

Published Online: 21 DEC 2007

DOI: 10.1002/9780470015902.a0006029.pub2

eLS

eLS

How to Cite

Nijtmans, L., van den Heuvel, L. and Smeitink, J. A. 2007. Oxidative Phosphorylation System: Nuclear Genes and Genetic Disease. eLS. .

Author Information

  1. Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

Publication History

  1. Published Online: 21 DEC 2007

Abstract

The underlying mutations in nuclear genes that directly affect the mitochondrial oxidative phosphorylation system are now known. Advances in this area have profited from progress in various genome projects.

Keywords:

  • mitochondria;
  • respiratory chain;
  • nuclear gene defects;
  • human