Telomeres and Telomerase in Ageing and Cancer
Published Online: 28 SEP 2007
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Ouellette, M. M. and Choi, K. H. 2007. Telomeres and Telomerase in Ageing and Cancer. eLS. .
- Published Online: 28 SEP 2007
Telomeres protect the ends of chromosomes and shorten each time somatic human cells divide. As a consequence, cells enter senescence after a limited number of divisions. The enzyme telomerase expressed in cancer cells and renewal tissues can prevent the shortening of telomeres and extend cellular lifespan.