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Genetic Redundancy

  1. David C Krakauer

Published Online: 15 JUL 2008

DOI: 10.1002/9780470015902.a0006116.pub2

eLS

eLS

How to Cite

Krakauer, D. C. 2008. Genetic Redundancy. eLS. .

Author Information

  1. Santa Fe Institute, Santa Fe, New Mexico, USA

Publication History

  1. Published Online: 15 JUL 2008

This is not the most recent version of the article. View current version (9 DEC 2014)

Abstract

Genetic redundancy typically relates to the duplication of an open reading frame within a genome. Genetic redundancy is often inferred when the modification or deletion of a portion of genetic material in a duplicated genome results in minimal changes in trait or organismal phenotype in reference to the nonduplicated wildtype. This invariance has been attributed to buffering mechanisms promoted by duplicates and to a number of compensatory pathways independent of the duplicate. Most duplicates are rapidly lost from genomes by mutation and drift.

Keywords:

  • Robustness;
  • canalization;
  • genome architecture;
  • evodevo;
  • regulatory network;
  • evolution